Jan 14, 2019
A study suggesting dementia may be caused by leaky blood vessels in the brain was welcomed by the Alzheimer’s Society who said it could lead to earlier diagnosis and potential treatments.
A research team at the University of Southern California found that leaky capillaries turned out to be early onset indicators of Alzheimer’s disease, signaling cognitive impairment before the hallmark toxic protein buildup begins.
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Study from Nature Medicine
14 January 2019
Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction
Daniel A. Nation, Melanie D. Sweeney, Axel Montagne, Abhay P. Sagare, Lina M. D’Orazio, Maricarmen Pachicano, Farshid Sepehrband, Amy R. Nelson, David P. Buennagel, Michael G. Harrington, Tammie L. S. Benzinger, Anne M. Fagan, John M. Ringman, Lon S. Schneider, John C. Morris, Helena C. Chui, Meng Law, Arthur W. Toga & Berislav V. Zlokovic
Nature Medicine (2019) | Download Citation