Muscadine Grape seeds and skins are rich in these antioxidants, including ellagic acid, resveratrol, quercetin, anthocyanins, flavonoids, Oligomeric Proanthocyanidin Complexes (OPCs) and many more, proven to better your overall health. See below articles about these Antioxidants: Oligomeric proanthocyanidin complexes (OPCs) Oligomeric proanthocyanidin complexes (OPCs) are a type of flavonoid that cannot be manufactured synthetically. They are known for their powerful antioxidative benefits that are 20 times greater than vitamin E and 50 times greater than vitamin C. It has been scientifically proven that OPCs are an active agent for the strengthening of the cardiovascular system. They strengthen blood vessel health and function, keeping them flexible and strong so that oxygen and nutrients flow throughout the body. At the same time, this helps ensure that waste material and CO2 can flow harmlessly out of the bloodstream and body. OPCs also inhibit enzymes that breakdown collagen, stabalise vitamin C (the building block of collagen), helping to maintain collagen levels. By maintaining collagen levels, our blood vessel system is also well supported. OPCs can be found in grape's skin and seed, wine, berries and pine bark, which are not commonly taken on a daily basis. Known as the discoverer of OPCs, Professor Jack Masquelier was the first person to have identified and isolated OPCs in 1948. He was able to harness the power of specific OPCs to deliver powerful antioxidant protection and support overall vascular health. Through his research, he developed a breakthrough ingredient - Masquelier's® Original OPCs; the world's first, widely researched and scientifically proven OPC that combines a unique and rich complex of OPCs and essential phytonutrients. Oligomeric proanthocyanidin complexes (OPCs) 10 Benefits of Grape Seed Extract, Based on Science https://www.healthline.com/nutrition/grape-seed-extract-benefits Oligomeric proanthocyanidin complexes (OPCs) Oligomeric proanthocyanidin complexes (OPC) exert anti-proliferative and pro-apoptotic effects on prostate cancer cells†‡ https://onlinelibrary.wiley.com/doi/abs/10.1002/pros.20829 Proanthocyanidins Benefits, Side Effects & Supplement Dosages https://nootriment.com/proanthocyanidins-benefits/ Oligomeric proanthocyanidin complexes: history, structure, and phytopharmaceutical applications https://pubmed.ncbi.nlm.nih.gov/10767669/ Proanthocyanidins: A comprehensive review https://www.sciencedirect.com/science/article/pii/S0753332219305359 ANTHOCYANINS https://www.verywellhealth.com/the-scoop-on-anthocyanins-89522 What Are Anthocyanins? https://www.verywellhealth.com/the-scoop-on-anthocyanins-89522 Health Benefits of Anthocyanins and Their Encapsulation for Potential Use in Food Systems: A Review https://pubmed.ncbi.nlm.nih.gov/25745811/ Anthocyanins: A Comprehensive Review of Their Chemical Properties and Health Effects on Cardiovascular and Neurodegenerative Diseases https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504512/ FLAVONOIDS https://www.healthline.com/health/what-are-flavonoids-everything-you-need-to-know ELLAGIC ACID https://www.life-enthusiast.com/articles/ellagic-acid-to-oncologists/ https://www.cancertutor.com/ellagicacid/ https://www.bensnaturalhealth.com/blog/ellagic-acid/ RESVERATROL 11 Amazing Benefits of Resveratrol https://healthyfocus.org/resveratrol-benefits/ (1) http://www.ncbi.nlm.nih.gov/pubmed/25761413 (2) http://www.ncbi.nlm.nih.gov/pubmed/16507749 (3) http://circ.ahajournals.org/content/111/2/e10 (4) http://www.ncbi.nlm.nih.gov/pubmed/20357044 (5) http://www.medicalnewstoday.com/releases/265726.php (6) http://www.neurology.org/content/early/2015/09/11/WNL.0000000000002035.short (7) http://onlinelibrary.wiley.com/doi/10.1002/mnfr.200700185/abstract (8) http://www.ncbi.nlm.nih.gov/pubmed/20472894 (9) http://link.springer.com/article/10.1007%2Fs12272-008-1124-7 (10) http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2012.230490/abstract (11) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679110/ (12) https://academic.oup.com/jid/article/191/10/1719/790275 (13) https://www.sciencedirect.com/science/article/pii/S0166354206002002?via%3Dihub (14) https://www.sciencedirect.com/science/article/abs/pii/S1043661802909928 (15) https://www.hindawi.com/journals/av/2015/184241/#B4 (16) https://www.ncbi.nlm.nih.gov/pubmed/25153875 (17) https://www.nature.com/articles/srep10029 (18) https://www.ncbi.nlm.nih.gov/pubmed/17449884?dopt=Abstract&holding=npg (19) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852857/ (20) https://www.ncbi.nlm.nih.gov/pubmed/25445538 QUERCETIN https://www.verywellhealth.com/the-benefits-of-quercetin-89071